Introduction to nanomaterials
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Nanomaterials are materials synthesized at the nanoscale between 1-100nm. Their properties can differ greatly from their larger counterparts. For example, a gold coin is soft and yellow at normal scale but becomes hard and red at the nanoscale. Nanomaterials have many applications including in medicine for targeted drug delivery, in diagnostics like cancer detection, and in cosmetics like sunscreens with efficient UV protection. They can cross cell membranes and offer localized targeted delivery of drugs while maintaining drug solubility.
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nanotechnology in drug development.
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Nanomedicine
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1- Diagnosis and treatment of cancer
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change the very foundations of cancer diagnosis, treatment, and prevention”. We have
already seen how nanotechnology, an extremely wide and versatile field, can affect many
of its composing disciplines in amazingly innovative and unpredictable ways.
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Cancer is a disease caused by normal cells changing them so that they grow in an uncontrolled way.
The uncontrolled growth can cause problems in one or more of the following ways:
-spreading into normal tissues nearby.
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external appearance of cancerous tumors, which have branch-like projections that
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1. The document discusses the history and development of nanotechnology from 1959 to the present, including important discoveries and inventions such as the scanning tunneling microscope.
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The document summarizes the history and development of nanotechnology. It discusses how the concept was first developed by Richard Feynman in 1959, and the term was coined by Norio Taniguchi in 1974. It then outlines key milestones and advancements in the 1980s and beyond that helped establish nanotechnology as a field, including the invention of the scanning tunneling microscope in 1981 and discoveries of fullerenes in 1985 and carbon nanotubes. The document also provides examples of how nanotechnology is being applied in biology and medicine, such as using atomic force microscopes to image cells, optical tweezers to manipulate organisms, and quantum dots for labeling parasites.
Bio-Nanotechnology
This document discusses the application of nanotechnology in biomedical fields such as drug delivery, gene delivery, and tissue engineering. It provides background on the history and definition of nanotechnology. It then discusses various nanomaterials that can be used for targeted drug and gene delivery such as liposomes, polymeric micelles, dendrimers, and nanoparticles. It also describes how microfluidics and nanomaterials can be applied to sperm sorting, oocyte handling, embryo culture, and metabolomics. Overall, the document outlines the current and potential future uses of nanotechnology in biomedicine.
Future prospects of nanobiotechnology
Nanobiotechnology has many potential applications in areas like medicine, genomics, and robotics. It offers novel opportunities for molecular disease imaging, targeted drug delivery, and therapeutic intervention. Some key areas of focus are using nanoparticles for controlled drug release, protein-based drug delivery systems, magnetic nanoparticles for imaging and therapy, and gene delivery vectors like liposomes and dendrimers. Nanotechnology also has applications in cancer research, cardiovascular disorders, neuroscience, molecular diagnostics, and gene therapy. It provides tools for protein analysis, single-cell studies, and tissue engineering scaffolds. Overall, nanobiotechnology holds promise for advancing healthcare through applications in various areas of medicine and biotechnology.
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Bionanotechnology introduction
This document discusses the history and concepts of bionanotechnology. It begins by outlining some of the early pioneers of nanotechnology, including Richard Feynman in the 1950s, Richard Smalley who developed buckyballs in the 1990s, and Eric Drexler who founded the field of molecular nanotechnology. It then defines bionanotechnology as the application of nanotechnology to biological and biomedical areas. The document discusses opportunities and challenges of bionanotechnology, such as using quantum dots for imaging and developing targeted drug delivery systems, while noting challenges like understanding long-term health impacts. It also outlines some key applications and features of nanotechnology for drug delivery.
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Bionanotechnology
Bionanotechnology involves utilizing biological systems at the nanoscale to develop functional nanostructures for various applications. It includes self-assembled nanostructures, bio-inspired materials, and using biological entities like viruses, ferritin proteins and DNA as templates to build nano-devices. Some key applications of bionanotechnology discussed are in medicine for targeted drug delivery, disease diagnosis, artificial photosynthesis, water treatment and military surveillance. However, developing this technology responsibly with consideration of ethical, legal and social implications will be important for public acceptance.
Nanotechnology in diagnostic Pathology
Nanotechnology offers promising applications in diagnostic pathology through the use of nanoscale devices and materials. Some key applications discussed in the document include using cantilevers to detect cancer biomarkers, nanopores for efficient DNA sequencing, nanotubes to map DNA mutations, nanoshells that absorb light for cancer treatment, dendrimers for drug delivery, magnetic nanoparticles as MRI contrast agents, quantum dots as fluorescent probes, and graphene oxide sheets for attaching antibodies for medical diagnosis. Overall, nanotechnology enables detection, imaging, and analysis at the molecular level for early disease diagnosis and targeted treatment.
Nanomedicine
Nanomedicine involves monitoring, repairing, constructing and controlling human biological systems at the molecular level using engineered nanodevices and nanostructures. It can be used for diagnosis, prevention and treatment of disease. Current areas of nanomedicine development include drug delivery, biopharmaceutics, implantable materials and devices, and diagnostic tools. Nanomedicine shows promise for a variety of medical applications and may offer more economical and effective ways to diagnose and treat disease in the future.
Nanobiotechnology
Nanobiotechnology involves the manipulation of matter at the nanoscale (1-100 nanometers) for applications in biology. Key developments include the atomic force microscope in 1980, which enabled imaging at the atomic level. Nanoparticles such as quantum dots have been used for in vivo cell imaging due to their strong fluorescent signals. Nanodevices have the potential to improve cancer detection and diagnosis by entering cells to determine which are cancerous. They may also preserve patient samples and make tests faster. Challenges include assessing the toxicity and biocompatibility of nanomaterials. Overall, nanobiotechnology could lead to new biomaterials and analytical tools with applications in medicine such as targeted drug delivery and disease diagnosis and treatment.
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Recent advances in nanotherapeutics from aissms college of pharmacy
Recent advances in nanotherapeutics from aissms college of pharmacy
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Principles of Nanobiotechnology. ppt.ppt
Nanobiotechnology uses nanotechnology to analyze and engineer biological systems at the nanoscale level. The document provides an overview of key concepts in nanobiotechnology including:
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Introduction to Nanobiotechnology note.pdf
Nanobiotechnology combines nanotechnology and biotechnology to build and manipulate devices at the nanoscale for studying and engineering biological systems. It allows characterization of biological structures and functions at the nanoscale level. Key applications of nanobiotechnology include developing nanoprobes, nanoparticles, and nanodevices for applications in diagnostics, therapeutics, drug delivery, and tissue engineering in the fields of biology and medicine. Some examples discussed are using nanoparticles for imaging and drug delivery, developing nanosensors for cancer detection, and exploring the use of nanorobots for targeted drug delivery and tissue repair.
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This document discusses various nanotechnology approaches for drug delivery, including nanoparticles for encapsulating and delivering drugs. It describes several types of nanoparticles - lipid-based, polymer-based, metallic, biological - that can be used for targeted drug delivery. It also highlights some achievements of nanotechnology in developing improved drug formulations, as well as challenges in the field and priority research areas like cancer nanotechnology.
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Nanotechnology involves working at the nanoscale of 1-100 nm to create novel materials and devices. It has many applications in medicine such as more effective drug delivery through nanocarriers that can target tissues. The document outlines various nanoscale drug delivery methods and nanotechnology applications in healthcare including cancer treatment, diagnostics, and overcoming challenges like biological degradation and improving targeting and patient compliance.
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Nano materials for cancer therapy.pptx (seminar).pptx by me
Nano materials show promise for more targeted cancer treatments with fewer side effects. Nanoparticles can be programmed to selectively destroy cancer cells without harming healthy cells, allowing patients to recover more quickly. Various nano structures under research include gold-coated silica nano shells for targeted drug delivery, dendrimers that can combine imaging, targeting and drug functions, and superparamagnetic nanoparticles for magnetic resonance imaging and targeting via magnetic fields. Applications include using quantum dots for optical detection, carbon nanotubes for biomarker detection, and nano sponges for sustained drug release at tumor sites. Overall, nano technologies may enable more effective cancer diagnostics and treatments with less toxicity.
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Nanotechnology involves engineering materials and devices on the nanoscale (1-100 nm) and can be applied to diagnostic pathology. It allows for early disease detection by taking advantage of nanoparticles' high surface area and ability to interact with biomolecules. Common nanodiagnostic techniques include magnetic nanoparticles for MRI contrast, nanochips for DNA analysis, microfluidics to automate biochemical assays, and nanoarrays for high-throughput screening of proteins and nucleic acids. Future applications may integrate multiple functions like imaging, detection, targeted drug delivery, and treatment monitoring into single nanodevices.
Applications of nano technology in pharmacy
Nanotechnology is the science dealing with processes at the molecular level and nano length scale. There are numerous natural examples like DNA and viruses. Pharmaceutical nanotechnology provides nano-materials and nano-devices. Nano-materials include those used in implants and tissue scaffolds, and can be nano-crystalline or nano-structured. Nano-devices are miniature devices at the nano scale used for applications like biosensing and detection. Nanotechnology has many applications in pharmacy including drug delivery, molecular diagnostics, biosensing, and gene therapy by overcoming limitations of conventional systems and enabling targeted and controlled delivery.
NANO TECHNOLOGY IN DRUG DELIVERY SYSTEM
Nanotechnology uses structures sized 100 nm or smaller to develop drug delivery systems. Nanoparticles made from metals, lipids, polymers, or biological materials can encapsulate drugs and transport them in the body. Lipid nanoparticles like liposomes are biocompatible and protect drugs, allowing targeted delivery. Polymer nanoparticles like dendrimers and micelles also encapsulate drugs. Nanotechnology overcomes obstacles like the blood-brain barrier and can uniformly deliver drugs while sustaining their release and preventing degradation. Problems in drug delivery like poor oral availability are addressed through these nanoscale drug carriers.
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2) Nanoparticles can help protect drugs from degradation and control their release in the body over extended time periods, improving compliance. This allows drugs to be administered less frequently.
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Bionanotechnology applies nano/microfabrication tools and processes to build devices for studying biosystems at the nanoscale. Researchers learn from biology to create new micro-nanoscale devices. It sits at the interface between chemical, biological, and physical sciences. Molecular biologists help nanotechnologists understand and access biological nanostructures and nanomachines. Antibody-nanoparticle modeling investigates interfacial properties of these bio-nano systems using computer simulations. Nanomedicines, such as lipid or polymer nanoparticles, are taken up by cells and can deliver drugs. DNA is used in molecular nanotechnology and nanorobotics due to its stiffness and self-assembly properties. Nanopore technology detects single molecules of
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This document discusses how nanotechnology can be used to detect cancer. It describes how nanoparticles like gold nanoparticles, quantum dots, and nanorobots could be engineered to target cancer cells for detection and treatment. Gold nanoparticles in particular can accumulate in tumors due to leaky vasculature and be used for imaging. Quantum dots consisting of materials like cadmium selenide can be conjugated to biomarkers to image different parts of cells. Future nanorobots may help distinguish cell types, deliver targeted radiation treatment, and be retrieved after their task is complete, representing a promising new approach to medicine.
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This document discusses the use of nanotechnology for cancer diagnosis and therapy. It begins by defining cancer and tumors, and then introduces nanotechnology and its applications in medicine including drug delivery, imaging, and cancer treatment. Specific nanoparticles discussed for cancer diagnosis include gold nanoparticles, bismuth sulfide nanoparticles, and iron oxide nanoparticles which can be used for computed tomography, magnetic resonance imaging, and ultrasound imaging, respectively. The document also discusses various nanoparticle-based approaches for detecting different types of cancer like bladder and breast cancer. In general, the document outlines how nanotechnology enables more precise cancer diagnosis and targeted therapy.
Nanotechnology
Nanotechnology deals with manipulating and controlling matter at the nanoscale, generally from 1 to 100 nanometers. It can be used to develop new materials, devices, and systems with applications in medicine, electronics, energy, and more. Some key applications of nanotechnology include using nanoparticles for targeted drug delivery in cancer treatment, developing stronger and lighter nanocomposite materials, improving solar cells and batteries, and enabling new detection and filtration systems. While nanotechnology holds promise, research is still needed to fully understand potential health and environmental risks from nanoparticles.
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Introduction to nanomaterials
- 2. Nanomaterials are the materials synthesize at nanoscaleand have dimensions between 1nm to 100nm Size of Nano 1 nm = 10-3 um = 10-6 mm = 10-9 m = 10-9 yard What are Nanomaterials? Example: DNA Size : 2-5nm
- 4. When we break this coin into small pieces on Nanoscale, the gold coin is no more yellow.
- 6. The breakthroughs of nanomaterials have remarkable applications in medicine and include: immuno-isolated nano porous implants with embedded pancreatic cells delivering insulin for diabetic patients polarity-based gated nanosieves for selected ion transport externally controlled nanoshell delivery vehicles for precision targeting single virus detectors gene engineered biological robots artificial RBCs. Nanomaterials in Drug Delivery
- 10. Tissue Engineering Drug development Diagnosis Detection of proteins New Biological devices Probing of DNA structrure Biodetection of pathogens Tumor destruction by Heating (hyperthermia) Biomedical Applications of Nanomaterials
- 11. Nanomaterials in Diagnosis and Treatment CantileversNanotubesQuantum DotsNanoshellsDendrimersFullerene-based DerivativesMonoclonal AntibodiesMagnetic NanoparticlesSolid Lipid Nanoparticles
- 14. anti-ageing creams with an increased intake of vitamins or enzymes
- 15. toothpastes
- 16. deodorants,
- 17. soaps,
- 18. shampoos,
- 21. moisturizers
- 22. lipsticks
- 23. foundations
- 24. face powders
- 25. Perfumes